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KMID : 0371420180950050278
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Annals of Surgical Treatment and Research
2018 Volume.95 No. 5 p.278 ~ p.285
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Kidney transplantation using expanded criteria deceased donors with terminal acute kidney injury: a single center experience in Korea
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Ko Kyung-Jai
Kim Young-Hwa
Kim Mi-Hyeong
Jun Kang-Woong
Kwon Kyung-Hye
Kim Hyung-Sook
Kim Sang-Dong
Park Sun-Cheol
Kim Ji-Il
Yun Sang-Seob
Moon In-Sung
Hwang Jeong-Kye
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Abstract
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Purpose: We investigated the clinical outcomes of deceased donor kidney transplantation (KT) using kidneys with terminal acute kidney injury (AKI).
Methods: Between February 2000 and December 2013, we performed 202 deceased donor renal transplants from 159 brain dead donors. According to the expanded criteria donor (ECD) and AKI network criteria, we divided 202 recipients into 4 groups: Group I: Non-AKI & standard criteria donor (SCD) (n = 97); group II: Non-AKI & ECD (n = 15); group III: AKI & SCD (n = 52); and group IV: AKI & ECD (n = 38).
Results: The incidence of delayed graft function (DFG) was significantly higher in patients with AKI than it was in the non-AKI group (P = 0.008). There were no significant differences among the 4 groups in graft survival (P = 0.074) or patient survival (P = 0.090). However, the long-term allograft survival rate was significantly lower in group IV than it was in other groups (P = 0.024).
Conclusion: Allografts from deceased donors with terminal AKI had a higher incidence of DGF than did those from donors without AKI. However, there is no significant difference in graft and patient survival rates among the groups. So, the utilization of renal grafts from ECDs with terminal AKI is a feasible approach to address the critical organ shortage.
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KEYWORD
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Acute kidney injury, Donor selection [E04.936.537.500], Kidney transplantation
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